Chinese scientists develop new technologies for embryo testing to make IVF healthier January 06, 2016 Source: Bio Valley The relevant research results were published in the international academic journal PNAS, and the scientists described the new technology and its scope of application in detail. Families who are unable to properly conceive their babies due to reproductive disorders often seek help from medical experts. They hope that doctors can help them overcome the problems they face. In some cases, in vitro fertilization is an ideal choice. During the in vitro fertilization process, the doctor will obtain the egg cells from the expectant mother through surgery, and then obtain the sperm from the prospective father, and perform sperm fusion in the laboratory. Once the egg cells are fertilized to form the fertilized egg, the doctor will implant it into the expectant mother. Or the uterus of other surrogates. But unfortunately, in some cases, this process can not always proceed as planned. If the expectant mother who provides the egg cell is over 40 years old, it is prone to abnormal chromosome number, resulting in aneuploidy, which ultimately makes in vitro fertilization impossible. Work properly. There are also other genetic mutations or gene deletions. In the past few years, scientists have developed different detection methods to detect aneuploidy or gene mutations, but until now, there are still no detection methods that can detect both cases at the same time, because it is very difficult to detect embryos, and it is easy to cause Other problems, so it is very important to be able to detect both aneuploidy and gene mutations. In this latest study, the researchers developed a new technique for simultaneous detection of both cases, using a second-generation sequencing method to analyze individual cell genomes, as well as aneuploidy and gene mutations. This technology has been successfully applied to two couples, one of these couples carrying mutations in disease-causing genes. Researchers can use this technology to remove embryos that carry mutations in disease-causing genes, helping unfertile parents to have healthy babies.
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