Release date: 2018-05-04 “To complete the mapping of the whole brain mesoscopic map of zebrafish with 200,000 neurons by 2020.†On May 2nd, the Xiangshan Science Conference held a special meeting of the International Cooperation Program for the Whole Brain Mesoscopic Neural Linkage Map. Academician and Director of the Institute of Neuroscience of the Chinese Academy of Sciences, Pu Muming, introduced that Chinese scientists will start from the model animal zebrafish to understand the working principle of the brain from the whole brain scale, and use the brain science research technology formed during the period to further complete the macaque whole brain in 2030. View map. "Mesoscopic" is between "macro" and "micro", studying the types and activities of neuronal cells at the nanometer and micrometer levels. "The zebrafish whole brain mesoscopic map does not only need to map the position of 200,000 neurons, but also complete the classification of neuronal cells, and determine the input and output activities of hundreds of neuronal cells, each of which completes at least 10 brains. Tracking of activities." Pu Muming said. It can be understood as drawing a neuron distribution map, determining "characters" (which tube movements, which tube emotions, which tube thinking), and determining the correspondence between actions or emotions and neuron "input" and "output". "The amount of data on meridian brain activity is huge. The high-level imaging and data analysis of 1 cubic millimeter of rat brain activity is performed with 50 nanometers as the high-edge slice. It takes 9 years to use existing instruments." According to researcher Han Hua, for this reason, the high-throughput SEM 3D imaging system with independent intellectual property rights is gradually improving the speed of imaging technology and recognition algorithms, and achieving high precision and speed. Using the platform, Du Jiulin, a researcher at the Institute of Neuroscience of the Chinese Academy of Sciences, completed the mapping of the whole brain nerve connection map of young zebrafish with a brain volume of about 0.5 mm3. "We can also capture the neural activity of zebrafish when they graze on paramecium in real time," Du Julin said. This breaks through two previous limitations. One is the tracking of all neuronal activity in the whole brain, and the other is that the study is awake zebrafish. Non-standard. "Next, we will study the correspondence between neural circuits and functions." In addition to zebrafish, the mapping of the more complex mouse brain and macaque brain is working in sync. The team of Luo Qingming, vice president of Huazhong University of Science and Technology, used the microscopic optical section tomography technique completed in 16 years to obtain a three-dimensional reconstruction map of whole brain and cell architecture, vascular network and neuronal morphology in mice. The somatic cloned monkeys born in China in January this year are regarded as experimental samples that define all gene sequences and can be mapped to the whole brain map of detectable markers. The human brain research has not yet “broken ice†and stays at the macro level of the brain. In 2018, Peking University published a high-quality large-scale Chinese brain fine structure template, so that the Chinese brain research does not need to be based on Western structural templates. "The clinical research of many Chinese doctors shows that the language area of ​​the Chinese brain is very different from the structural templates issued by Western countries, and it cannot be copied." Gao Jiahong, a professor at Peking University. Source: Technology Daily Tuna Loin,Frozen Tuna Loin,Fresh Tuna Loin,Yellowfin Tuna Loin ZHEJIANG RETRONX FOODSTUFF INDUSTRY CO.,LTD , https://www.retronxfoods.com