New contrast agents help detect millimeter-scale cancer tissue May 25, 2016 Source: Kexun Wood Heating Stove,Wood Burning Stove,Wood Pellet Stove,Fireplace Smokeless Pellet Stove Shandong Longze Mechanical Equipment Co.,Ltd , https://www.pelletmachinefactory.com
Contrast agent is one of the most commonly used chemicals in interventional radiotherapy, mainly used to display blood vessels, body cavities and the like. According to Japanese media reports, researchers at the National Institute of Radiation Medicine in Japan have developed a new type of contrast agent in which the particles are only 60 nanometers in diameter. In normal tissues, the contrast particles do not leak from the blood vessels, but There is a large hole in the vessel wall in the cancerous tissue, and this contrast agent will leak out of it.
In addition, the cancerous tissue is reduced in oxygen concentration to produce lactic acid, and the contrast agent particles are mixed with calcium phosphate and manganese ions which are dissolved by acidic substances, so when using this contrast agent for magnetic resonance imaging (MRI) examination, Detection of calcium phosphate and manganese ions, more clearly see cancer tissue. In the experiment, the microcancer tissue with a diameter of 1.5 mm on the liver of the experimental mouse was detected by using the contrast agent.
At the same time, because the more acidic the cancer tissue is more malignant, the contrast of the contrast can be used to determine the degree of malignancy of the cancer.
The researchers believe that the use of this contrast agent in the use of MRI is expected to determine the occurrence and metastasis of cancer as early as possible, and help to choose the appropriate treatment for the degree of cancer malignancy.
The research results were published on the online edition of the journal Nature·Nanotechnology magazine on the 17th.