:2019-06-24

Sina Technology News Beijing time on June 24th news, according to foreign media reports, a great news! Scientists have recently developed a laser that can detect and destroy cancer cells in the blood!

We all know that cancer cells can spread through the blood to other parts of the body. Now this new laser can detect and kill these tumor cells from the outside of the skin. Although the laser distance is still a distance from commercial diagnostic tools, its sensitivity It is 1000 times more powerful than the current method for detecting tumor cells in the blood.

To test whether a cancer spreads, doctors usually perform blood sample analysis, but such tests often fail and fail to detect tumor cells, especially when the patient is in the early stages of cancer.

If the test results are positive, it usually means that there are high concentrations of circulating tumor cells in the blood. When the results are detected, the tumor cells may have spread to other organs, and it is too late to effectively treat the patients.

A few years ago, scientists proposed an alternative, non-invasive method to detect more blood samples with higher sensitivity. They first performed multiple proficiency tests in the laboratory, then performed experiments on the animal's body, and recently on humans. The patient underwent a clinical trial.

The latest laser technology, called "Cytophone," uses laser pulses to bombard external skin and heat cells in the blood, but this laser only heats melanoma cells, not healthy cells, because melanoma cells carry light that can be absorbed. The melanin, which then uses ultrasound to detect the tiny waves emitted by this thermal effect.

The team used this technique to test 28 patients with superficial melanoma and 19 healthy individuals without melanoma who exposed the laser to the tester's hand and observed changes within 10 to 60 minutes. The technique identifies 27 patients with circulating tumors in 28 melanoma patients.

Discover and kill tumor cells

The experimental results show that the device does not return any false positive results to healthy people, nor does it cause safety concerns or side effects. Melanin is a pigment usually found in the skin, but the skin cells are not harmed, even if the skin naturally produces melanin. The laser technology also does not harm these cells because the laser scatters over a large area of ​​the skin and does not adequately focus on individual skin cells, causing damage.

Unexpectedly, the team also found that after treatment, cancer patients circulated fewer tumor cells, using only a relatively low laser dose, mainly for diagnosis rather than cancer, but even at this low level Under the laser energy, the laser beam seems to destroy cancer cells.

The working principle is this: when melanin absorbs heat, the water around the melanin in the cell begins to evaporate, creating a bubble that expands and ruptures, mechanically destroys the cells, and by killing these cells, prevents the spread of metastatic cancer. Further research will be carried out in the next step to further optimize the device and kill more tumor cells without harming other cells.

At present, the researchers have not tested people with dark skin and high levels of melanin. The team hopes to expand the application of this technology to find circulating tumor cells released by cancer other than melanoma.

These tumor cells do not carry melanin, so in order to detect them, researchers first need to inject special markers or molecules into the patient to bind them to the tumor cells so that they can be locked by the laser. To date, they have demonstrated that this technology can be used to treat breast cancer patients. (叶倾城)

Source: Sina Technology

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