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99% purity Cabozantinib /XL184 powder for Cancer treatment
Product Name:Â Cabozantinib Malate
Synonyms:Cabozantinib (S)-malate;Cabozantinib L-Malate Salt;N-[4-[(6,7-DiMethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxaMide (2S)-;Cabozantinib (S)-Malate(XL-184);Cabozantinib L-Malate;Cabozantinib Malate (XL184);XL-184 (Malate)
CAS: 1140909-48-3
MF: C32H30FN3O10
MW:635.5931032
Chemical Properties:Off-White Solid
Uses : Cabozantinib is a small molecule C-Met modulator. Cabozantinib acts as a potent multitargeted VEGFR2, Met, FLT3,Â
Cabozantinib Description:
Cabozantinib is a new molecular targeted drug developed by Exelixis Biopharmaceuticals in the United States. November 29, 2012 The US Food and Drug Administration (FDA) approved cabotibine for the treatment of unresectable malignant locally advanced or metastatic thyroid medullary carcinoma.
In addition, Sorafenib, Vandenebu, and Levignitavir are also approved by the Food and Drug Administration (FDA) for the treatment of advanced thyroid cancer.
COA:
Cabozantinib Malate Pharmacological Effects:
Â
Cabozantinib S-MALATE,formerly known as XL184, trade name Cabometyx, is developed by Exelixis biopharmaceutical company in the United States. The drug is mainly targeted at MET and VEGFR2 tyrosine kinases that associated with the growth and proliferation of prostate cancer, inhibiting tumor metastasis and angiogenesis. Cabozantinib S-MALATE , the malate of Cabozantinib, is an effective VEGFR2 inhibitor, and IC50 is 0.035 nM. It also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2 and AXL, and IC50 is 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM respectively.
Cabozantinib(Cometriq) was granted orphan drug status by the U.S. Food and Drug Administration (FDA) in January 2011. Cabozantinib(Cometriq) is approved by the U.S. FDA for medullary thyroid cancer. and advanced renal cell carcinoma in people who have received prior anti-angiogenic therapy. It is currently undergoing clinical trials for the treatment of prostate, bladder, ovarian, brain, melanoma, breast, non-small cell lung, pancreatic, and hepatocellular cancers.
 
 Our advantages:
 1.Our company is a professional raw powder factory in China for over 10  years, all powders are factory directly supplying.
 2. Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France,  Russia, USA, Australia, Japan, Korea      and many other countries, over 100kgs each month.
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 3.Professional team special for package and shipment and staring on tracking code 24hours for  customs pass guaranteed.      100% pass to UK, Norway, Poland, Spain, USA, Canada, Brazil;  98% pass to Germany, Russia, Australia, New ZealandÂ
  Most of powders are in stock, Chargeable samples are available, Could be shipped out within  24hours.
  High quality, good price, fast and safety delivery. Shipment by DHL, TNT, FEDEX, HKEMS,  UPS, etc.Â
Packing?
1. food bag packing
2. according to your suggestion
2. change the name to ship  your parcel
Â
99% purity Cabozantinib /XL184 powder for Cancer treatment
Product Name:Â Cabozantinib Malate
Synonyms:Cabozantinib (S)-malate;Cabozantinib L-Malate Salt;N-[4-[(6,7-DiMethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxaMide (2S)-;Cabozantinib (S)-Malate(XL-184);Cabozantinib L-Malate;Cabozantinib Malate (XL184);XL-184 (Malate)
CAS: 1140909-48-3
MF: C32H30FN3O10
MW:635.5931032
Chemical Properties:Off-White Solid
Uses : Cabozantinib is a small molecule C-Met modulator. Cabozantinib acts as a potent multitargeted VEGFR2, Met, FLT3,Â
Cabozantinib Description:
Cabozantinib is a new molecular targeted drug developed by Exelixis Biopharmaceuticals in the United States. November 29, 2012 The US Food and Drug Administration (FDA) approved cabotibine for the treatment of unresectable malignant locally advanced or metastatic thyroid medullary carcinoma.
In addition, Sorafenib, Vandenebu, and Levignitavir are also approved by the Food and Drug Administration (FDA) for the treatment of advanced thyroid cancer.
COA:
Cabozantinib Malate Pharmacological Effects:
Â
Cabozantinib S-MALATE,formerly known as XL184, trade name Cabometyx, is developed by Exelixis biopharmaceutical company in the United States. The drug is mainly targeted at MET and VEGFR2 tyrosine kinases that associated with the growth and proliferation of prostate cancer, inhibiting tumor metastasis and angiogenesis. Cabozantinib S-MALATE , the malate of Cabozantinib, is an effective VEGFR2 inhibitor, and IC50 is 0.035 nM. It also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2 and AXL, and IC50 is 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM respectively.
Cabozantinib(Cometriq) was granted orphan drug status by the U.S. Food and Drug Administration (FDA) in January 2011. Cabozantinib(Cometriq) is approved by the U.S. FDA for medullary thyroid cancer. and advanced renal cell carcinoma in people who have received prior anti-angiogenic therapy. It is currently undergoing clinical trials for the treatment of prostate, bladder, ovarian, brain, melanoma, breast, non-small cell lung, pancreatic, and hepatocellular cancers.
Â
 Our advantages:
 1.Our company is a professional raw powder factory in China for over 10  years, all powders are factory directly supplying.
 2. Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France,  Russia, USA, Australia, Japan, Korea      and many other countries, over 100kgs each month.
Â
 3.Professional team special for package and shipment and staring on tracking code 24hours for  customs pass guaranteed.      100% pass to UK, Norway, Poland, Spain, USA, Canada, Brazil;  98% pass to Germany, Russia, Australia, New ZealandÂ
  Most of powders are in stock, Chargeable samples are available, Could be shipped out within  24hours.
  High quality, good price, fast and safety delivery. Shipment by DHL, TNT, FEDEX, HKEMS,  UPS, etc.Â
Packing?
1. food bag packing
2. according to your suggestion
2. change the name to ship  your parcel
Â
Model NO.: 849217-68-1/1140909-48-3
Delivery Time: 4-7 Days
Express: TNT, FedEx, EMS, DHL(Door-to-Door)
Payment Terms: T/T, Western Union, Money Gram,Bitcoins
Mqq: 10gram
Markets: Global
Trademark: Quanao
Transport Package: Foil Bag or Tin, Perfect Discreet, as Required
Specification: ISO9001: 2008
Origin: Guangzhou
HS Code: 2942000000
Model NO.: 849217-68-1/1140909-48-3
Delivery Time: 4-7 Days
Express: TNT, FedEx, EMS, DHL(Door-to-Door)
Payment Terms: T/T, Western Union, Money Gram,Bitcoins
Mqq: 10gram
Markets: Global
Trademark: Quanao
Transport Package: Foil Bag or Tin, Perfect Discreet, as Required
Specification: ISO9001: 2008
Origin: Guangzhou
HS Code: 2942000000