Posted on

Model NO.: Pharmaceutical grade
Trademark: NEWBIO
Transport Package: Aluminum Foil Bags
Specification: SGS
Origin: China
HS Code: 0000000000
Model NO.: Pharmaceutical grade
Trademark: NEWBIO
Transport Package: Aluminum Foil Bags
Specification: SGS
Origin: China
HS Code: 0000000000
Small Molecular Erlotinib Hydrochloride
(CAS No.: 183319-69-9)

Chemical Information
Product Name Erlotinib hydrochloride
MF C22H24ClN3O4
MW 429.91
Storage Store at -20°C
Targets HER1            EGFR   
IC50 2 nM               2 nM

  Erlotinib hydrochloride 

 CAS 183319-69-9 Brand: NEWBIO
MF C22H24ClN3O4 EINECS:ND
MW  429.9 MOQ: 100grams
Product Categories: API;Molecular Targeted Antineoplastic;Heterocyclic Compounds;anti-neoplastic;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Usage Erlotinib hydrochloride (trade name Tarceva) is a drug used to treat non-small cell lung cancer (NSCLC), pancreatic cancer and several other types of cancer. It is a reversible tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR). It is marketed in the United States by Genentech and OSI Pharmaceuticals and elsewhere by Roche.
Applications Erlotinib hydrochloride , Pharmaceutical raw materials 

Description
Erlotinib HCl (OSI-744) is an EGFR inhibitor with IC50 of 2 nM in cell-free assays, >1000-fold more sensitive for EGFR than human c-Src or v-Abl.
 Erlotinib HCl (1 μM) induces apoptosis in DiFi humancolon cancer cells. Erlotinib inhibits growth of a panel of NSCLC cell lines including A549, H322, H3255, H358 H661, H1650, H1975, H1299, H596 with IC50 ranging from 29 nM to >20 μM. Erlotinib HCl(2 μM) significantly inhibits growth of AsPC-1 and BxPC-3 pancreatic cells. 
 
Application
Cells were treated with single dose of erlotinib (1 µM, 24 hours),  The greatest cell death was observed in the Txt->OSI-774->media sequence, while the cells treated with the OSI-774->Txt->media sequence resumed proliferation by 72hrs post-treatment. Cleaved PARP and Caspase-3 were detected in the sequence of Txt->OSI-774, and with simultaneous treatment, but not in the sequence of OSI-774->Txt. Further, cleaved PARP and Caspase-3 persisted to 72hrs after the Txt->OSI-774 treatment. These data support the previous results on sub-G1 cells, and molecularly demonstrate an apoptotic response.
Erlotinib had significant dose-dependent efficacy. In the 100mg/kg group there was growth inhibition of 61%. The other groups had the following growth inhibition: 25mg/kg: 46%; 12.5mg/kg: 36%; 6.25mg/kg: 28%. There were no partial or complete regressions.


FEATURED PRODUCT:
Wuhan Newbio Pharm-tech Co., Ltd.
S# CAS No. Product Name S# CAS No. Product Name
1  86639-52-3   25  183321-74-6 Erlotinib
2  154229-18-2 Abiraterone Acetate 26  183319-69-9 Erlotinib Hydrochloride
3  50-76-0 Actinomycin D 27  159351-69-6 Everolimus
4  106941-25-7 Adefovir 28  56296-78-7 Fluoxetine Hydrochloride
5  850140-72-6 Afatinib 29  184475-55-6  
6  330784-47-9 Avanafil 30  136572-09-3  
TriHydrate
7  319460-85-0 Axitinib 31  1441674-54-9 Ledipasvir(Acetone)
8  1421373-66-1 AZD-9291 (Mesylate) 32  191732-72-6 Lenalidomide
9  123524-52-7 Azelnidipine 33  21672   
10  863031-21-4 Azilsartan Medoxomil 34  76144-81-5 Mildronate
11  179324-69-7   35  474645-27-7 Monomethyl Auristatin E
12  357336-20-0 Brivaracetam 36  63121-00-6  
13  842133-18-0 Canagliflozin 49  33069-62-4  
14  928672-86-0 Canagliflozin HemiHydrate 37  137281-23-3 Pemetrexed Disodium
15  41575-94-4   38  53123-88-9 Rapamycin
16  50935-04-1 Carubicin 50  135062-02-1 Repaglinide
17  288383-20-0 Cediranib 39  945667-22-1 Saxagliptin Hydrate
18  15663-27-1   40  709031-78-7 Saxagliptin Hydrochloride
19  877399-52-5 Crizotinib 41  486460-32-6 Sitagliptin
20  171500-79-1 Dalbavancin 42  654671-77-9 Sitagliptin Phosphate Hydrate
21  114977-28-5   44  85622-93-1 Temozolomide
22  148408-66-6   45  477600-75-2 Tofacitinib
23  25316-40-9   46  540737-29-9 Tofacitinib Citrate
24  133040-01-4 Eprosartan 47  170791-09-0 Trityl Candesartan Cilexetil

ABOUT DELIVERY:
#1 Products can be sent out within 24 hours after payment. 
#2 Secure and discreet shipment. 
#3 Various methods for your choice, like DHL/FedEx/SF-express.

OUR COMMITMENT:
#1 We are manufacturer with own factory and we sale this product at a best quality and low price.
#2 All product listed is available in stock, please contact the sale for more details.
#3  We have QA&QC department to guarantees the quality, product pass rate can reach 100%. 


CONTACT US:
Telephone +86-027-87002705
Mobile +86-13277093700
  newbiopharmtech
FaceBook Page https://www.facebook.com/newbiopharma/
Facebook Group https://www.facebook.com/groups/1739616069613416/
Website http://www.newbiopharm.com/
Online Store http://biocar.en.made-in-china.com/



 
Small Molecular Erlotinib Hydrochloride
(CAS No.: 183319-69-9)

Chemical Information
Product Name Erlotinib hydrochloride
MF C22H24ClN3O4
MW 429.91
Storage Store at -20°C
Targets HER1            EGFR   
IC50 2 nM               2 nM

  Erlotinib hydrochloride 

 CAS 183319-69-9 Brand: NEWBIO
MF C22H24ClN3O4 EINECS:ND
MW  429.9 MOQ: 100grams
Product Categories: API;Molecular Targeted Antineoplastic;Heterocyclic Compounds;anti-neoplastic;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Usage Erlotinib hydrochloride (trade name Tarceva) is a drug used to treat non-small cell lung cancer (NSCLC), pancreatic cancer and several other types of cancer. It is a reversible tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR). It is marketed in the United States by Genentech and OSI Pharmaceuticals and elsewhere by Roche.
Applications Erlotinib hydrochloride , Pharmaceutical raw materials 

Description
Erlotinib HCl (OSI-744) is an EGFR inhibitor with IC50 of 2 nM in cell-free assays, >1000-fold more sensitive for EGFR than human c-Src or v-Abl.
 Erlotinib HCl (1 μM) induces apoptosis in DiFi humancolon cancer cells. Erlotinib inhibits growth of a panel of NSCLC cell lines including A549, H322, H3255, H358 H661, H1650, H1975, H1299, H596 with IC50 ranging from 29 nM to >20 μM. Erlotinib HCl(2 μM) significantly inhibits growth of AsPC-1 and BxPC-3 pancreatic cells. 
 
Application
Cells were treated with single dose of erlotinib (1 µM, 24 hours),  The greatest cell death was observed in the Txt->OSI-774->media sequence, while the cells treated with the OSI-774->Txt->media sequence resumed proliferation by 72hrs post-treatment. Cleaved PARP and Caspase-3 were detected in the sequence of Txt->OSI-774, and with simultaneous treatment, but not in the sequence of OSI-774->Txt. Further, cleaved PARP and Caspase-3 persisted to 72hrs after the Txt->OSI-774 treatment. These data support the previous results on sub-G1 cells, and molecularly demonstrate an apoptotic response.
Erlotinib had significant dose-dependent efficacy. In the 100mg/kg group there was growth inhibition of 61%. The other groups had the following growth inhibition: 25mg/kg: 46%; 12.5mg/kg: 36%; 6.25mg/kg: 28%. There were no partial or complete regressions.


FEATURED PRODUCT:
Wuhan Newbio Pharm-tech Co., Ltd.
S# CAS No. Product Name S# CAS No. Product Name
1  86639-52-3   25  183321-74-6 Erlotinib
2  154229-18-2 Abiraterone Acetate 26  183319-69-9 Erlotinib Hydrochloride
3  50-76-0 Actinomycin D 27  159351-69-6 Everolimus
4  106941-25-7 Adefovir 28  56296-78-7 Fluoxetine Hydrochloride
5  850140-72-6 Afatinib 29  184475-55-6  
6  330784-47-9 Avanafil 30  136572-09-3  
TriHydrate
7  319460-85-0 Axitinib 31  1441674-54-9 Ledipasvir(Acetone)
8  1421373-66-1 AZD-9291 (Mesylate) 32  191732-72-6 Lenalidomide
9  123524-52-7 Azelnidipine 33  21672   
10  863031-21-4 Azilsartan Medoxomil 34  76144-81-5 Mildronate
11  179324-69-7   35  474645-27-7 Monomethyl Auristatin E
12  357336-20-0 Brivaracetam 36  63121-00-6  
13  842133-18-0 Canagliflozin 49  33069-62-4  
14  928672-86-0 Canagliflozin HemiHydrate 37  137281-23-3 Pemetrexed Disodium
15  41575-94-4   38  53123-88-9 Rapamycin
16  50935-04-1 Carubicin 50  135062-02-1 Repaglinide
17  288383-20-0 Cediranib 39  945667-22-1 Saxagliptin Hydrate
18  15663-27-1   40  709031-78-7 Saxagliptin Hydrochloride
19  877399-52-5 Crizotinib 41  486460-32-6 Sitagliptin
20  171500-79-1 Dalbavancin 42  654671-77-9 Sitagliptin Phosphate Hydrate
21  114977-28-5   44  85622-93-1 Temozolomide
22  148408-66-6   45  477600-75-2 Tofacitinib
23  25316-40-9   46  540737-29-9 Tofacitinib Citrate
24  133040-01-4 Eprosartan 47  170791-09-0 Trityl Candesartan Cilexetil

ABOUT DELIVERY:
#1 Products can be sent out within 24 hours after payment. 
#2 Secure and discreet shipment. 
#3 Various methods for your choice, like DHL/FedEx/SF-express.

OUR COMMITMENT:
#1 We are manufacturer with own factory and we sale this product at a best quality and low price.
#2 All product listed is available in stock, please contact the sale for more details.
#3  We have QA&QC department to guarantees the quality, product pass rate can reach 100%. 


CONTACT US:
Telephone +86-027-87002705
Mobile +86-13277093700
  newbiopharmtech
FaceBook Page https://www.facebook.com/newbiopharma/
Facebook Group https://www.facebook.com/groups/1739616069613416/
Website http://www.newbiopharm.com/
Online Store http://biocar.en.made-in-china.com/



 

Various products of Boxes of Wolfberry King, providing product images and basic parameters with each Bulk Boxes Goji Juice Concentrate and Boxes Goji  Concentrate; Fresh wolfberry due to different producing areas and different color, but the color is very soft, shiny, full of meat; and dyed medlar mostly in the previous year's Chen goods, from the point of view of fleshy, matte appearance But very bright and attractive, so when buying wolfberry must not be greedy "color." In particular, the whole wolfberry dyed red, even the wolfberry pedicle where the white spots are also red, but most of the normal medlar tip pedicle mostly yellow or white, with pigment dipped wolfberry pedicle was red, with sulfur Baked dark brown. As the pigment dyed medlar particularly afraid of water, it is recommended that you buy a few wolfberry medlar can be put in the water, or deliberately with a wet hand rub a rub, if there is fade, it shows the use of pigment.We are a professional Chinese supplier of Boxes Goji Concentrate, and look forward to your cooperation!


Boxes Of Wolfberry King

Boxes Of Wolfberry King,Luxury Boxes Of Wolfberry King,Wholesale Boxes Of Wolfberry King,Packaging Box Of Wolfberry King

Ningxia ZhongYuanDa Agel Ecommerce Ltd. , http://www.freshwolfberry.com