On Monday, Nature published the results of a team of Dr. Zhang Xiang, a Chinese scientist at Baylor College of Medicine in the United States. Dr. Zhang first discovered the interaction mechanism between the human immune system and tumor blood vessels, which may change the researchers' treatment of cancer. Ideas. In 1971, Judah Folkman (1933-2008), a pediatric surgeon at Boston Children's Hospital at Harvard University, published an article on subversion of traditional cognition in the top medical journal New England Journal of Medicine. Based on his many years of thinking and research data, Folkman It is believed that cancer cells will release some signals during the growth process, promote new blood vessels to grow into tumors, and provide nutrients for tumor growth. Based on this theory, Folkman believes that the use of anti-angiogenic therapies may treat cancer. Dr. Zhang Xiang This theory seems to be taken for granted today, but at the time, most experts in the field of cancer research thought it was a whimsy of Folkman. In 2003, 32 years later, Folkman's "starved to death tumor" therapy based on Folkman's tumor neovascular theory was named the top ten technological breakthroughs of the year by Science. Recent studies have shown that although cancer cells produce many new blood vessels in order to obtain oxygen and nutrients, these new blood vessels are defective, and they not only have leakage, but also have structural and functional defects. This defect in neovascularization creates a very malicious tumor microenvironment (low oxygen content, low pH), and cancer cells can enter the blood vessels more easily and turn on distant metastasis. Traditional anti-angiogenic drugs mainly inhibit angiogenesis or destroy the newly formed blood vessels, so as to block the motive of tumor stealing nutrients and achieve the purpose of starvation. Endo-type chemotherapy is one of the first-line treatments for advanced non-small cell lung cancer in China. The picture on the left is the blood vessels of healthy tissue; the picture on the right is the blood vessels that are incomplete in the tumor tissue, and the cancer cells can easily enter and pass through the bloodstream. Fire Cabinet,Fire Hose Cabinet,Fire Control Cabinet,Fire Fighting, JIANGSU NEW FIRE FIGHTING TECHNOLOGY CO.,LTD , https://www.newayfire.com
