Release date: 2014-12-25 A study published online in Nature-Immunology published a new class of potent, widely used antibodies that neutralize dengue viruses. This is the first study to reveal that new antibodies can neutralize all four types of viruses, including those found in mosquitoes, and this discovery may help develop effective vaccines against the disease. Dengue fever is an emerging viral infection that spreads rapidly through mosquitoes and affects approximately 400 million people each year. The regional spread of dengue fever has continued to expand, threatening South America and Australia, and is said to be likely to spread to southern Europe. One of the dengue-infected viruses, even if the body is healed, has only a lifetime immune effect on the infected virus and no immunity against other types of dengue viruses. In addition, because the outer shell of dengue virus changes greatly during its life cycle, the identification of viruses by antibodies is also complicated. Therefore, it is urgent to understand the immune response of the human body after infection with dengue virus and the response after vaccination. Gavin Screaton et al. analyzed a number of monoclonal antibodies obtained from dengue patients. They discovered a novel antibody that efficiently neutralizes the virus, which binds to an epitope that is newly found in all dengue virus envelopes. In laboratory tests, the researchers found that the antibody recognizes the epitope and effectively neutralizes viruses in insects and human cells. The discovery made it possible to turn efficient, widely used antibody development into a realistic target for vaccines and opened the way for the development of generic dengue vaccines. Source: bio360 Fresh Cut Sliced Porcini,Boletus Porcini Fine Cut,Fresh Ceps Porcini,Porcini Edible Mushrooms Guangyun Agricultural Biotechnology (Jiangsu) Co., Ltd , https://www.7-mushrooms.com
A study published online in Nature-Immunology published a new class of potent, widely used antibodies that neutralize dengue viruses. This is the first study to reveal that new antibodies can neutralize all four types of viruses, including those found in mosquitoes, and this discovery may help develop effective vaccines against the disease.