Researchers at the National Nanotechnology Laboratory (LNNano) in Brazil have developed a biosensor that detects molecules associated with neurodegenerative diseases and certain types of cancer. This sensor is actually a single-layer organic nano-transistor coated on a glass slide, a reduced form (GSH) containing glutathione, and a specific reaction can occur when exposed to glutathione S transferase (GST), GST It is associated with diseases such as Parkinson's disease, Alzheimer's disease and breast cancer. The reaction between GSH-GST can be detected by the transistor and can be used for diagnostic purposes. The main purpose of this project is to collaborate with experts in different fields of research to develop devices that can make instant diagnoses, using versatile materials to create simple sensors and microfluidic systems for rapid diagnosis. Carlos Cesar Bof Bufon, a director of LNNano's Functional Equipment and Systems Laboratory (DSF) and a member of the group, said that platforms like this device can be used to make rapid, safe and relatively inexpensive diagnostics for complex diseases. Nanosystems are used to identify meaningful molecules in the analyte. The subject was chaired by Professor Lauro Kubota of the Institute of Chemistry at the University of Campinas (IQ-UNICAMP). In addition to its small size and low price, the advantages of this nanosensor include high sensitivity to the detection molecules. Bufon said that this is the first time that organic transistor technology has been applied to detect GSH-GST responses, which is important for diagnosing diseases such as neurodegenerative diseases. Even if the target molecule is low in the analyte, the device can detect it, thanks to nano-sensing technology. Nano means one billionth of a meter or a millionth of a centimeter. The system can also be adapted to detect other substances, such as molecules associated with different diseases, or elements present in contaminated materials. This requires replacing the molecules in the sensor with molecules that can react with other target chemicals. The research team is experimenting with paper as a substrate to further reduce sensor prices, improve portability and ease of manufacturing and processing. The problem is that the paper is usually insulated. Bufon has developed a technology that allows paper to be made conductive while immersing cellulose fibers in a conductive polymer solution, while transmitting sensory data. The basis of this technology is the in situ synthesis of conductive polymers. Since such a polymer cannot be retained on the surface of the paper, it is necessary to synthesize these polymers in the voids of the cellulose fibers and in the middle of the voids. This can be achieved by gas phase chemical polymerization: the liquid oxidant is allowed to penetrate into the paper and the paper is then exposed to the gas phase monomer. A monomer is a low molecular weight molecule that reacts with itself or other low molecular weight molecules to form a high molecular weight polymer. The monomer vaporizes under the paper and penetrates into the submicron fiber voids. The polymerization is started by mixing the monomer with the oxidant in the void, and the entire paper is impregnated completely. This polymer paper obtains the conductivity of the polymer, and depending on the purpose of the application, the conductivity can also be adjusted by manipulating the elements embedded in the cellulose. Thus the device can be electrically conductive, the fluid can pass without significant loss, or it can be a semiconductor that reacts with certain molecules as a physical, chemical or electrochemical sensor. Black Tarary Buckwheat Flour,Black Tarry Buckwheat Flour,Tartary Buckwheat Instant Powder ,Black Tartary Buckwheat Instant Powder Huantai Biotechnology Co., Ltd. , https://www.huantaifds.com