Expert: Antiviral mechanism is more active when cell nutrition is insufficient March 31, 2017 Source: Xinhuanet Professor Xu Pinglong from the Institute of Life Sciences of Zhejiang University found that when the cells are undernutrition, the antiviral mechanism of the organism is more active; if the cells are too rich, it will reduce the antiviral immune function of the body, and the virus will also enter the market. This discovery will provide a drug target for antiviral therapy. According to the researchers, in life, signal transmission occurs between cells and cells at all times to complete each of our life activities. When the virus invades the cells, certain proteins in the cytoplasm of the human body can actively detect the viral nucleic acid, and then initiate a series of anti-viral mechanisms in the cells, and transmit the signals to the surrounding cells, reminding everyone to "combat." This cellular mechanism constitutes an important barrier for the living body to resist the virus and maintain human health. "Like humans use language to talk, the 'language' of intracellular communication is a series of receptors, adaptor proteins, kinases, transcription factors, effector proteins, etc." Xu Pinglong said that there is a key kinase "TBK1" in the cytoplasmic nucleic acid recognition pathway. It can induce downstream signals to trigger cells to synthesize a series of antiviral factors, thereby establishing the antiviral status of themselves and surrounding cells. Xu Pinglong said that after adjusting the cell population by artificially increasing or decreasing the number of cells, the research team found that when cells change from crowded to loose, their antiviral ability will decrease, and cell nutrition stress or crowded each other will help improve cells. Virus defense capabilities. The work also revealed that the "Hippo pathway" is a key cellular mechanism regulating cell proliferation and migration, and the level and activity of components can be used as a determinant of the regulation of host antiviral response intensity. Researchers believe that these components can be used as targets for antiviral drugs. Related papers were published online March 27 in the journal Nature Cell Biology. Hydraulic Power Unit,Hydraulic Pump Unit,Hydraulic Power Station,Power Unit,Hydraulic Poppet Valve,Hydraulic Pilot Valve Changzhou Satidi Import and Export Co., Ltd. , https://www.guanjiejts.com