Release date: 2016-05-04 New therapies are getting closer. Image source: BSIP/UIG New options have been evading scientists' investigations, but now scientists have finally discovered that a natural hormone made up of fat cells can help people fight diabetes and obesity. By analyzing the genes of two patients with neonatal premature aging (NPS, which causes patients with low fat), the Atul Chopra team at Baylor College of Medicine in Houston, Texas, found that these patients were lifeless because they lacked A previously unknown gene that the researchers named asprosin. “We studied this extremely rare disease and found a gene that could benefit millions of people with diabetes.†Mouse experiments have shown that this hormone plays an important role in determining blood sugar levels, especially between meals. "Asprosin is released by fat cells and can reach the liver, telling the liver to release glucose to the blood immediately." When the blood sugar level rises, the hormone production process is turned off. Because these two NPS patients lack the mechanism to increase the amount of sugar in the blood between the three meals, they feel tired and weak. “I don’t often feel hungry.†Abigail Solomon, who helped solve this puzzle, said, “I eat a lot, and often eat sugary foods first, then protein.†Diabetes researchers are very interested in this discovery. "Asprosin reaches the liver and causes glucose overproduction, an important feature of type 2 diabetes, which makes the study even more interesting," said Alan Cherrington, a diabetes expert at Vanderbilt University in Tennessee. “My dream is to enable patients who rely on insulin to reduce or stop using the drug,†Chopra said. “Or you can provide anti-asprosin antibodies to diabetics every week to lower their blood sugar levels, which means patients can Reduce or completely stop using insulin." Chopra's team has registered a patent for this hormone and is now testing an antibody that inhibits asporsin. "We are treating diabetic mice and it seems to work now," he said. The team hopes to begin human clinical trials within two or three years. Asprosin can also play a role in the treatment of obesity. The Chopra team found that obese people had twice as much blood sugar levels as non-obese people. "Our next study will focus on obesity," he said. "It is very likely that the level of Asprosin will rise after the obesity index rises." Source: Chinese Journal of Science Berberine Hydrochloride Tablets Berberine Hydrochloride Tablets,Berberine Hydrochloride Tablet,Intestinal Infection Diarrhea,Treatment Of Intestinal Infection SHANDONG XINHUA PHARMACEUTICAL Co., Ltd. , https://www.sdxinhuapharm.com