Release date: 2016-01-20 The reporter learned from the Institute of Biochemistry and Cell Biology of the Shanghai Academy of Sciences, Chinese Academy of Sciences that the team of Huilijian and the Ding Yitao team of the Affiliated Drum Tower Hospital of Nanjing University successfully designed a new bio-artificial liver system based on “hiHep cellsâ€. Significantly improve the survival rate of liver failure pigs, and hope to continue the life of patients with liver failure. The relevant results were published on the 16th in the internationally renowned academic journal Cell Research. At the beginning of the year, the team had launched the first clinical treatment of “hiHep cells†bioartificial liver, successfully treating a patient with liver failure. In 2016, the team will conduct further clinical research in Shanghai and its surrounding areas. For severe liver failure, in addition to liver transplantation, there is currently no effective treatment. In response, scientists have proposed a treatment using a bioartificial liver system to provide liver function to patients. Bioartificial liver is an external liver function support system that can promote the recovery of autologous liver function in patients with liver failure. It can also gain time for patients planning liver transplantation and wait for a suitable liver source. The core technology of bioartificial liver is functional hepatocytes for treatment. At present, bioartificial liver developed at home and abroad mainly uses porcine primary hepatocytes or human hepatoma cells as a source of functional hepatocytes. However, these cells have large defects in safety or in terms of functionality, which seriously depresses the clinical application of bioartificial liver. Therefore, obtaining new functional liver cells is a key step in promoting the clinical application of bioartificial liver. In this study, scientists filled "hiHep cells" into bioartificial liver and observed their treatment of pigs with acute liver failure. The experimental results show that untreated acute liver failure pigs generally die in about 3 days, while the survival rate of acute liver failure pigs treated with "hiHep cells" bioartificial liver is 80%. After survival, the pig's indicators gradually returned to normal levels. According to researcher Hui Lijian, the liver is similar to a "chemical plant", which itself has the functions of biosynthesis and metabolic detoxification. If the liver cells have been depleted, in the case of almost loss of these functions, the doctor can participate in the normal liver function activities of the human body by means of some foreign liver cells, which can help the patient to go through an extremely difficult and dangerous period. This study demonstrates for the first time that the bio-artificial liver system based on “hiHep cells†is effective and safe in large animal treatment experiments, which provides a solid foundation for further clinical research in the next step. At present, China has become the world's largest social cost for hepatitis B, cirrhosis and liver cancer. Experts predict that the research results of the new bioartificial liver system are expected to significantly improve the survival time of patients, and strive for more rescue time for liver treatment and liver replacement. Source: Guangzhou Daily We're professional Sterilization Cases
manufacturers and suppliers in China, specialized in providing high
quality medical instruments with reasonable price. We warmly welcome you
to buy or wholesale bulk Sterilization Cases for sale here and get quotation from our factory. Sterilization Cases,Sterilization Container,Sterilisation Container,Sterilization Containers Surgical Instruments Tonglu WANHE Medical Instrument Co., Ltd , https://www.vanhurhealth.com